Ciba Foundation Symposium - Adrenergic Mechanisms by with J.R. Vane Edited by G.E.W. Wolstenholme & Maeve

By with J.R. Vane Edited by G.E.W. Wolstenholme & Maeve O'Connor

Content:
Chapter 1 starting handle (pages 1–5): Sir Henry Dale
Chapter 2 Formation of Adrenergic Transmitters (pages 6–16): H. J. Schumann
Chapter three Formation of Adrenaline and Noradrenaline (pages 17–27): Norman Kirshner
Chapter four The destiny of Adrenaline and Noradrenaline (pages 27–39): Julius Axelrod
Chapter five 3?Methoxy?4?Hydroxymandelic Acid Excretion in Phaeochromocytoma (pages 40–44): M. Sandler and C. R. J. Ruthven
Chapter 6 The Metabolism of [??14C](±)?Adrenaline within the Cat (pages 45–60): Norman Kirshner
Chapter 7 Chairman's starting feedback (pages 61–62): H. Blaschko
Chapter eight beginning, improvement and Distribution of Chromaffin Cells (pages 63–82): J. D. Boyd
Chapter nine The garage of Amines within the Chromaffin mobilephone (pages 83–99): Paul Hagen and Russell J. Barrnett
Chapter 10 a few Observations at the Synthesis and garage of Catechol Amines within the Adrenaline?Containing Cells of the Suprarenal Medulla (pages 100–102): A. Bertler, N. A. Hillarp and E. Rosengren
Chapter eleven mobilephone kinds of the Adrenal Medulla (pages 103–110): Olavi Eranko
Chapter 12 Chairman's starting comments (pages 111–115): J. H. Gaddum
Chapter thirteen liberate of Sympathetic Transmitter via Nerve Stimulation (pages 116–130): G. L. Brown
Chapter 14 Interference with the discharge of Transmitter in accordance with Nerve Stimulation (pages 131–147): W. A. Bain
Chapter 15 the results of Bretylium and Allied brokers on Adrenergic Neurones (pages 148–157): A. F. Green
Chapter sixteen The endurance of Adrenergic Nerve Conduction After TM IO or Bretylium within the Cat (pages 158–161): okay. A. Exley
Chapter 17 a few Pharmacological homes of Guanethidine (pages 162–172): H. J. Bein
Chapter 18 results of Adrenaline, Noradrenaline and Isopropylnoradrenaline in guy (pages 173–189): Jean Ginsburg and A. F. Cobbold
Chapter 19 results of Catechol Amines on Consecutive Vascular Sections (pages 190–200): Bjorn Folkow
Chapter 20 medical results of gear which forestall the discharge of Adrenergic Transmitter (pages 201–208): D. R. Laurence and M. L. Rosenheim
Chapter 21 Bretylium (pages 209–219): R. W. D. Turner
Chapter 22 Chairman's beginning feedback: the concept that of Receptors (pages 220–222): H. O. Schild
Chapter 23 Relationships among Agonists, Antagonists and Receptor websites (pages 223–245): B. Belleau
Chapter 24 Receptors for Sympathomimetic Amines (pages 246–252): Robert F. Furchgott
Chapter 25 Sympathomimetic medicines and Their Receptors (pages 253–263): E. J. Ariens
Chapter 26 a variety of different types of Receptors for Sympathomimetic medicines (pages 264–274): E. J. Ariens
Chapter 27 Biophysical adjustments Produced by way of Adrenaline and Noradrenaline (pages 275–287): Edith Bulbring
Chapter 28 impact of Adrenaline on Depolarized tender Muscle (pages 288–294): H. O. Schild
Chapter 29 The Relation of Adenosine?3?, 5??Phosphate to the motion of Catechol Amines (pages 295–304): E. W. Sutherland and T. W. Rall
Chapter 30 The motion of Adrenaline on Carbohydrate Metabolism on the subject of a few of Its Pharmacodynamic results (pages 305–322): Lennart Lundholm and Ella Mohme?Lundholm
Chapter 31 Chairman's starting comments (pages 323–325): U. S. von Euler
Chapter 32 Tyramine and different Amines as Noradrenaline?Releasing components (pages 326–336): J. H. Burn
Chapter 33 a few Observations at the results of Tyramine (pages 337–355): P. A. Nasmyth
Chapter 34 The activities of Sympathomimetic Amines on Tryptamine Receptors (pages 356–372): J. R. Vane
Chapter 35 The Depolarizing and blocking off motion of Amphetamine within the Cat's more advantageous Cervical Ganglion (pages 373–381): H. Reinert
Chapter 36 Chairman's commencing comments (pages 382–385): Marthe Vogt
Chapter 37 a few crucial activities of Adrenaline and Noradrenaline while Administered into the Cerebral Ventricles (pages 386–392): Floyd R. Domer and W. Feldberg
Chapter 38 Intervention of an Adrenergic Mechanism in the course of mind Stem Reticular Activation (pages 393–409): P. Dell
Chapter 39 Electrophysiological facts with regards to the function of Adrenaline within the vital frightened process (pages 410–420): P. B. Bradley
Chapter forty The Passage of Catechol Amines during the Blood?Brain Barrier (pages 421–423): H. Weil?Malherbe
Chapter forty-one unlock of an Adrenaline?Like Substance through electric Stimulation of the mind Stem (pages 424–431): E. Marley
Chapter forty two at the Biochemistry and attainable services of Dopamine and Noradrenaline in mind (pages 432–439): Arvid Carlsson, Margit Lindqvist and Tor Magnusson
Chapter forty three Awakening activities of Derivatives of Phenylalanine (pages 440–445): T. L. Chrusciel
Chapter forty four medical results of Amine Oxidase Inhibitors (pages 446–453): R. T. C. Pratt
Chapter forty five medical effects with Monoamine Oxidase Inhibitors in Psychiatry (pages 454–462): Arno Voelkel
Chapter forty six brief conversation: particular Antagonism of Dibenamine to Ergometrine (pages 463–465): H. Konzett
Chapter forty seven brief verbal exchange: Adrenergic Mechanisms in irritation (pages 466–468): D. A. Willoughby and W. G. Spector
Chapter forty eight Thermoregulation in baby Animals (pages 469–471): R. E. Moore
Chapter forty nine Chairman's final comments (page 472): J. H. Burn
Chapter 50 Chairman's beginning feedback (pages 473–480): H. Blaschko
Chapter fifty one brief communique: a few difficulties about the garage of Catechol Amines within the Adrenal Medulla (pages 481–501): N. A. Hillarp
Chapter fifty two brief communique: a brand new Adrenergic Mechanism (pages 502–537): J. H. Burn
Chapter fifty three Observations at the Localization of Noradrenaline in Homogenates of Dog's Hypothalamus (pages 539–543): T. L. Chrusciel
Chapter fifty four Synthesis of Catechol Amines within the Depleted mind (pages 544–587): H. Weil?Malherbe
Chapter fifty five Chairman's precis (pages 588–594): J. H. Gaddum

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Of 45 75 f r a c t i o n s 25 m~.. 0 . OM gradient. OM t o Basic F r a c t i o n s I 6. OM gradient. I Conjugates DOMA MOMA Adrenaline Metanephrine unknown DOPEC MGPEG FIG. I. Flow sheet of the fractionation procedure for the catabolites of adrenaline. E 0 100 Cot Trenled With 150 Mg. V. hr. Urine Cat Treated With Pyrogallol 6 hr. Urine . 2. Separation of IRC-50 eluates on Whatman No. I filter paper. Solvent butanol saturated with 1N-hydrochloric acid.

1956). Proc. exp. Bid. ),93, S . , and VOGT,M. (1958). ]. Physiol. ), 141,132. , and D’IORIO,A. (1957). ]. , 35, 151. SCHAUMANN, W. (1958). Nairnyri-Schrriiedeberg’s Arch. exp. Path. , 235, 1. SCHUMANN,H. J. (1956). Narrnyn-Schnziedeberg’s Arch. exp. Path. , 227, 566. SCHUMANN, H. J. (1958a). Narrnyn-Schmiedeberg’s Arch. exp. Path. , 234, 17. SCHUMANN, H. J. (1958b). Nai~tiyn-Schrrtiedeber~’sArch. exp. Path. , 233, 296. SCHUMANN, H. J. (1959). Naunyn-Schnriedeberg’s Arch. exp. Path. , 236, 474.

226, 213. , and KIRSHNER, N. (1958). Circulation, 17, 366. KIRSHNER, N. (1959). Fed. , 18, 261. ,and GOODALL, McC. (1957). J. biol. , 226, 207. , and KAUFMAN, S. (1959). Fed. , 18, 272. LEVIN,E. , CREVELING, C. , and WITKOP,B. (1959). J. Amer. chem. ,81, 62 and 63. , COOPER, J. , CLARK, C. , and BAER,J. E. (1953). Science, 117,663. , CREVELING, C. , and UDENFRIEND, s. (1958). Science, 127, 648. DISCUSSION Bacq: One of my former collaborators, Walter Verly, has studied the origin in the rat of the methyl group of the adrenaline found in the suprarenals (1956.

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