Asymmetric Catalysis on Industrial Scale.. Challenges, by Blaser H.U., Schmidt E. (eds.)

By Blaser H.U., Schmidt E. (eds.)

Show description

Read or Download Asymmetric Catalysis on Industrial Scale.. Challenges, Approaches and Solutions PDF

Best chemistry books

Synthetic Inorganic Chemistry. A Course of Laboratory And Classroom Study For First Year College Students

This is often an actual copy of a booklet released earlier than 1923. this isn't an OCR'd publication with unusual characters, brought typographical mistakes, and jumbled phrases. This ebook can have occasional imperfections comparable to lacking or blurred pages, terrible photographs, errant marks, and so forth. that have been both a part of the unique artifact, or have been brought by way of the scanning technique.

Inorganic Ring Systems

Content material: up to date advancements in inorganic ring platforms / J. -F. Labarre (France) -- Phosphorus (III)-nitrogen ring compounds / R. Keat (U. okay. ) -- Sulfur-nitrogen anions and similar compounds / T. Chivers, R. T. Oakley (Canada) -- Homocyclic sulfur molecules / R. Steudel (FRG) -- Cyclic selenium sulfides / R.

Additional info for Asymmetric Catalysis on Industrial Scale.. Challenges, Approaches and Solutions

Sample text

1995, 117, 9375. 7 J. Halpern in Asymmetric Synthesis, Vol. 5, Chiral Catalysis (J. D. ), Academic Press, New York, 1985, chap. 2: Asymmetric Catalytic Hydrogenation: Mechanism and Origin of Enantioselection. 39 2 The Other L-Dopa Process Rçdiger Selke Abstract In January 1986 Isicom, a prescription drug used to treat the Parkinson syndrome, went on sale in the former German Democratic Republic.

1999, 64, 1947. 19 I New Processes for Existing Active Compounds Asymmetric Catalysis on Industrial Scale: Challenges, Approaches and Solutions Edited by H. U. Blaser, E. Schmidt Copyright ° 2004 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim ISBN: 3-527-30631-5 23 1 Asymmetric Hydrogenations ± The Monsanto L-Dopa Process William S. Knowles Abstract The development of catalysts for asymmetric hydrogenation began with the concept of replacing the triphenylphosphane ligand of the Wilkinson catalyst with a chiral ligand.

This modest result, of course, was of no preparative value, but it did establish that the hydrogenation technique gave a definite asymmetric bias. In order to achieve this bias, the hydrogen atom, the ligand, and the substrate all had to be on the metal at the same time. Furthermore, we established that the hydrogenation was accomplished in solution and not from some extraneous rhodium plating out in our reactor. The inherent generality of the method offered almost unlimited opportunities for matching substrate and catalyst, moving towards the goal of achieving efficient results.

Download PDF sample

Rated 4.78 of 5 – based on 34 votes