By Henri Ulrich
Cumulenes are natural molecules with or extra cumulative (consecutive) double bonds. Their reactions usually continue at room temperature, without or with a catalyst, and are stereospecific, giving the response items in excessive yields – good points attribute of “click reactions”.
Cumulenes in click on Reactions presents a finished record of cumulene platforms and their reactions, with an emphasis on their “click-like” nature. The chapters are established in response to the variety of carbon atoms within the procedure, together with assurance of:
- introduction to the chemistry of cumulenes
- one-carbon cumulenes: sulfines, sulfenes, thiocarbonyl S-imides, thiocarbonyl S-sulfides, and 1-aza-2-azoniaallene salts
- two-carbon cumulenes: carbon oxides, carbon sulfides, carbon nitrides (isocyanates, isothiocyanates, and carbodiimides), phosphaallenes, and diarsaallenes
- 1,2-dicarbon cumulenes: ketenes, thioketenes, ketenimines, 1-silaallenes, 1-phosphaallenes, and different steel allenes
- 1,3-dicarbon cumulenes: thiocarbonyl S-ylides, 2-azaallenium salts, 1-oxa-3-azoniabutatriene salts, 1-thia-3-azoniabutatriene salts, and phosphorous ylides
- 1,2,3-tricarbon cumulenes: allenes, butatrienes, greater cumulenes and heterobutatrienes
- noncarbon cumulenes: azides, triazaallenium salts, sulfur oxides, sulfur nitrides, N-sulfinylamines, sulfurdiimides, and dithionitronium cation
Cumulenes in click on Reactionsis a vital consultant for researchers and complex scholars in academia and examine operating in artificial natural, inorganic and bioorganic chemistry.Content:
Chapter 1 common advent (pages 1–12):
Chapter 2 1?Carbon Cumulenes (pages 13–44):
Chapter three 2?Carbon Cumulenes (pages 45–241):
Chapter four 1,2?Dicarbon Cumulenes (pages 243–390):
Chapter five 1,3?Dicarbon Cumulenes (pages 391–398):
Chapter 6 1,2,3?Tricarbon Cumulenes (pages 399–473):
Chapter 7 Noncarbon Cumulenes (pages 475–540):
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Extra info for Cumulenes in Click Reactions
The carbonylative ring expansion of aziridines with carbon monoxide is accomplished in the presence of rhodium complexed dendrimers to afford β-lactames 63 in quantitative yields 77 . R2 R2 + CO N R1 NR1 O 63 In the reaction of the aziridine 64 with CO in the presence of Co2 (CO)8 in DME at 100 ◦ C the β-lactame 65 is obtained in 94 % yield 78 . Et H Et H + CO N N O PhCH2CH2 CH2CH2Ph 64 65 The reaction is regiospecific with carbonyl insertion into the less substituted of the two ring carbon–nitrogen bonds.
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