Cumulenes in Click Reactions by Henri Ulrich

By Henri Ulrich

Cumulenes are natural molecules with or extra cumulative (consecutive) double bonds. Their reactions usually continue at room temperature, without or with a catalyst, and are stereospecific, giving the response items in excessive yields – good points attribute of “click reactions”. 

Cumulenes in click on Reactions presents a finished record of cumulene platforms and their reactions, with an emphasis on their “click-like” nature. The chapters are established in response to the variety of carbon atoms within the procedure, together with assurance of:

  • introduction to the chemistry of cumulenes
  • one-carbon cumulenes: sulfines, sulfenes, thiocarbonyl S-imides, thiocarbonyl S-sulfides, and 1-aza-2-azoniaallene salts
  • two-carbon cumulenes: carbon oxides, carbon sulfides, carbon nitrides (isocyanates, isothiocyanates, and carbodiimides), phosphaallenes, and diarsaallenes
  • 1,2-dicarbon cumulenes: ketenes, thioketenes, ketenimines, 1-silaallenes, 1-phosphaallenes, and different steel allenes
  • 1,3-dicarbon cumulenes: thiocarbonyl S-ylides, 2-azaallenium salts, 1-oxa-3-azoniabutatriene salts, 1-thia-3-azoniabutatriene salts, and phosphorous ylides
  • 1,2,3-tricarbon cumulenes: allenes, butatrienes, greater cumulenes and heterobutatrienes
  • noncarbon cumulenes: azides, triazaallenium salts, sulfur oxides, sulfur nitrides, N-sulfinylamines, sulfurdiimides, and dithionitronium cation

Cumulenes in click on Reactionsis a vital consultant for researchers and complex scholars in academia and examine operating in artificial natural, inorganic and bioorganic chemistry.Content:
Chapter 1 common advent (pages 1–12):
Chapter 2 1?Carbon Cumulenes (pages 13–44):
Chapter three 2?Carbon Cumulenes (pages 45–241):
Chapter four 1,2?Dicarbon Cumulenes (pages 243–390):
Chapter five 1,3?Dicarbon Cumulenes (pages 391–398):
Chapter 6 1,2,3?Tricarbon Cumulenes (pages 399–473):
Chapter 7 Noncarbon Cumulenes (pages 475–540):

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The carbonylative ring expansion of aziridines with carbon monoxide is accomplished in the presence of rhodium complexed dendrimers to afford β-lactames 63 in quantitative yields 77 . R2 R2 + CO N R1 NR1 O 63 In the reaction of the aziridine 64 with CO in the presence of Co2 (CO)8 in DME at 100 ◦ C the β-lactame 65 is obtained in 94 % yield 78 . Et H Et H + CO N N O PhCH2CH2 CH2CH2Ph 64 65 The reaction is regiospecific with carbonyl insertion into the less substituted of the two ring carbon–nitrogen bonds.

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